What is Sibutrex?

Sibutrex is indicated for the management of obesity, including weight loss and maintenance of weight loss, and should be used in conjunction with a reduced calorie diet. Sibutrex is recommended for obese patients with an initial body mass index > 30 kg/m2 or > 27 kg/m2 in the presence of other risk factors (e.g. hypertension, diabetes, dyslipidemia). Body mass index is calculated by taking the patient's weight, in kg, and dividing by the square of the height of the patient, in metres.

How Sibutrex Works?

If you eat an excessive amount of food of fat or calories, the excess is stored as fat by the body, resulting in weight gain. When you eat fat, your body breaks it down into its simplest components so that it can be digested.Sibutrex medicine works in your digestive system to block about one-third of the fat in the food you eat from being digested.Sibutrex attaches to the lipases and blocks them from breaking down some of the fat you have eaten.


How Sibutrex taken?

The recommended starting dose of Sibutrex is 10 mg once daily with or without food. If there is inadequate weight loss, the sibutrex dose may be titrated after four weeks to a total of 15 mg once daily.Sibutrex doses above 15 mg daily are not recommended. The Sibutrex 5 mg dose should be reserved for patients who do not tolerate the Sibutrex 10 mg dose. Blood pressure and heart rate changes should be taken into account when making decisions regarding dose titration.

What are the Sibutrex side-effects?

The Sibutrex side-effects are usually mild and don't last longer than a few hours. These are as follows

Dry mouth.

Anorexia.

insomnia.

constipation.

Diarrhea.

Flatulence.

Gastroenteritis, peripheral oedema.

Arthritis, agitation, hypertonia.

Bronchitis, pruritis and menstrual disorders.

Warning And Precautions

Sibutrex is strictly taken under doctor's supervision.

Do not take Sibutrex tablets after a high-fat meal.

Let your doctor know your medical history before taking Sibutrex medication.

The use of sibutrex and excess alcohol is not recommended.

Sibutrex should not be used concomitantly with monoamine oxidase inhibitors (MAOI) and serotonergic drugs (selective serotonin reuptake inhibitors) since rare, but serious, constellation of symptoms termed ‘serotonin syndrome’ have been reported.

Sibutrex substantially increases blood pressure in some patients. Hence regular monitoring of blood pressure is required when prescribing sibutrex.

Sibutrex should be used cautiously in patients with a history of seizures. It should be discontinued in any patient who develops seizures.

Sibutrex medicine does not suppress appetite; rather, it helps create a sense of fullness, causing the patient to feel physically satisfied with less food than usual.

Sibutrex may increase blood pressure and heart rate in some patients and may cause serious health complications when in combination with certain other drugs;Sibutrex medication should be taken exactly as directed by a doctor.

In case of Sibutrex overdose, please contact your local poison control center or hospital immediately for more information about Sibutrex medicine.